High seroprevalence of Epstein-Barr virus in children with multiple sclerosis.

نویسندگان

  • D Pohl
  • B Krone
  • K Rostasy
  • E Kahler
  • E Brunner
  • M Lehnert
  • H-J Wagner
  • J Gärtner
  • F Hanefeld
چکیده

We studied seroprevalence and concentrations of Epstein-Barr virus (EBV) antibodies in 147 pediatric patients with multiple sclerosis (MS) and paired controls. The children with MS showed a near-complete seropositivity for EBV antibody against virus capsid antigen (98.6% vs 72.1% in controls, p = 0.001) but did not display serologic evidence for a recent EBV infection. EBV antibody concentrations of pediatric patients with MS were significantly higher vs controls.

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عنوان ژورنال:
  • Neurology

دوره 67 11  شماره 

صفحات  -

تاریخ انتشار 2006